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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2A
All Species:
31.82
Human Site:
Y177
Identified Species:
46.67
UniProt:
P13861
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13861
NP_004148.1
404
45518
Y177
G
D
D
G
D
N
F
Y
V
I
E
R
G
T
Y
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
Y251
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
F
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
Y235
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
Y
Dog
Lupus familis
XP_541890
401
45078
Y174
G
D
D
G
D
N
F
Y
V
I
E
R
G
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
P12367
401
45371
Y174
G
D
D
G
D
N
F
Y
V
I
E
R
G
T
Y
Rat
Rattus norvegicus
P12368
401
45522
Y174
G
D
D
G
D
N
F
Y
V
I
E
R
G
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
Y120
V
G
R
C
V
G
N
Y
D
N
R
G
S
F
G
Chicken
Gallus gallus
Q5ZM91
382
43332
G172
V
I
Q
Q
G
D
E
G
D
N
F
Y
V
V
D
Frog
Xenopus laevis
NP_001084637
402
45172
Y176
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
Y
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
Y174
G
D
D
G
D
N
F
Y
V
I
E
R
G
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
G158
I
I
R
Q
G
D
D
G
D
N
F
Y
V
I
E
Honey Bee
Apis mellifera
XP_392905
383
43849
V164
D
D
G
D
N
F
Y
V
I
E
R
G
K
F
E
Nematode Worm
Caenorhab. elegans
P30625
366
41449
G156
I
I
E
Q
G
E
E
G
D
N
F
Y
V
I
D
Sea Urchin
Strong. purpuratus
Q26619
369
41770
G155
V
I
D
Q
G
D
D
G
D
N
F
Y
V
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
R194
K
L
D
S
D
S
K
R
L
V
I
N
C
L
E
Red Bread Mold
Neurospora crassa
Q01386
385
42138
E176
V
V
E
K
G
R
F
E
V
Y
V
N
S
T
G
Conservation
Percent
Protein Identity:
100
58.4
61.1
91
N.A.
86.8
86.8
N.A.
58.6
35.1
64.8
71.2
N.A.
48.7
49.7
32.9
52.2
Protein Similarity:
100
68.3
70.7
94.5
N.A.
91.3
92
N.A.
69
52.7
80.6
83.6
N.A.
67.8
69
54.9
69
P-Site Identity:
100
86.6
93.3
100
N.A.
100
100
N.A.
6.6
0
93.3
93.3
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
6.6
100
93.3
N.A.
6.6
26.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.2
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
57
63
7
57
19
13
0
32
0
19
0
0
0
19
% D
% Glu:
0
0
13
0
0
7
13
7
0
7
32
0
0
0
19
% E
% Phe:
0
0
0
0
0
7
57
0
0
0
25
0
0
13
7
% F
% Gly:
50
7
7
50
32
7
0
25
0
0
0
13
50
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
25
0
0
0
0
0
0
7
50
7
0
0
19
0
% I
% Lys:
7
0
0
7
0
0
7
0
0
0
0
0
7
0
0
% K
% Leu:
0
7
0
0
0
0
0
0
7
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
50
7
0
0
32
0
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
25
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
7
0
7
0
0
13
50
0
0
0
% R
% Ser:
0
0
0
7
0
7
0
0
0
0
0
0
13
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% T
% Val:
25
7
0
0
7
0
0
7
57
7
7
0
25
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
57
0
7
0
25
0
0
44
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _